| Characteristic | Details |
|---|---|
| Chemical Name | Pregabalin |
| Common Dosage | 75 mg, 150 mg, 300 mg |
| Therapeutic Class | Anticonvulsant |
| Route of Administration | Oral |
| Half-Life | 6.3 hours |
| Learn More About Pregabalin |
Chemical Structure
Pregabalin is a gamma-aminobutyric acid (GABA) analog. Its formula is C8H17NO2. Its molecular weight is 159.23 g/mol. Pregabalin’s structure includes a pentanoic acid core with an isobutyl group. It binds to the alpha2-delta subunit of voltage-gated calcium channels in the CNS. This reduces neurotransmitter release, easing neuropathic pain and seizures. Its enantiomeric purity ensures consistency in its pharmacological actions.
Dosage Information
Pregabalin’s dosage varies based on indication. For neuropathic pain, initial dosing often starts at 150 mg per day. Maximum dose can reach 600 mg daily, divided into two or three doses. For epilepsy, doses align similarly. For fibromyalgia, starting doses are generally lower. Patients should adjust their intake gradually to assess tolerability. Physicians often recommend 75 mg twice daily initially. Individual response and tolerability dictate dosage adjustments.
Pregabalin Precautions
Before initiating treatment, consider potential side effects. Dizziness and somnolence are common. Pregabalin 150 mg may affect motor skills; caution is advised when driving. It’s crucial to monitor for any allergic reactions. Patients with kidney impairment should exercise caution. Dose adjustments are necessary for renal function variations. Alcohol intensifies some side effects. Careful monitoring is essential during treatment initiation and adjustment phases.
Missed Dose
In cases where a dose is missed, take the missed dose immediately when remembered. If it’s close to the next scheduled dose, skip it. Avoid doubling up on doses to compensate. Regular dosing enhances therapeutic effects. Maintaining a consistent schedule ensures optimal medication efficacy.
Pregabalin Signs and Symptoms of Overdose
Overdose signs are significant. Patients may experience dizziness, somnolence, or confusion. Increased heart rate and elevated blood pressure could occur. Immediate medical intervention is crucial in suspected overdose cases. Intensive monitoring may be required. Promptly seek medical advice if overdose symptoms present.
Pregabalin Over The Counter
Pregabalin 150 mg is not available over the counter. It’s a prescription medication. Physicians prescribe it based on specific clinical conditions. It treats epilepsy, neuropathic pain, and fibromyalgia. Regulatory authorities control its distribution. This ensures patient safety and appropriate use.
- Pregabalin treats epilepsy and neuropathic pain.
- It requires a prescription for use.
- Side effects include dizziness and somnolence.
Pregabalin remains a vital pharmaceutical agent for managing specific conditions. Its precise mechanism within the CNS offers relief for patients. Proper dosing and monitoring are essential. Understanding its chemical structure and pharmacokinetics aids in its therapeutic use. Adherence to prescribed regimens maximizes its efficacy while minimizing potential risks.
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